News

The newfound bone marrow could play a significant role in understanding various bone diseases

Mar, 2021 - By WMR

The newfound bone marrow could play a significant role in understanding various bone diseases

Researchers have discovered a new type of bone marrow, which can change understanding of conditions such as osteoporosis.

By taking their microscopes to human bones, scientists in Australia have discovered a completely new type of bone marrow, which they believe could play a vital role in the development of various bone diseases. The new cell mutates many different genes, gives new light to the way bone breaks down and transforms and opens up new possibilities for the treatment of conditions such as osteoporosis.

As part of natural bone growth, specialized facial cells break down old bone cells and rebuild them. When mutations occur in this cycle and substances are discarded, conditions such as bone fragility and osteoporosis may subside, instead of the different cells involved in this process may offer new ways of intervention. Among them is a type of cell called osteoclasts, which are specialized cells that break down bone tissue and serve as the first research center at the University Of New South Wales (UNSW). They used what is known as intravital imaging technology to look inside living bone tissue, where they found that osteoclasts were actually divided into very small cells, before turning into osteoclasts again.

Following these findings, the team collaborated with scientists at Imperial College London to remove 40 of these genes from experimental models, finding that 17 of them had an effect on bone size and strength. These genes have been found to be linked to genetic variation known to play a role in bone mineral density and to develop conditions such as skeletal dysplasia, indicating the importance of the role of osteomorphs. As an example of this, the group believes that these cells may be a key factor in some of the most common complications associated with the treatment of osteoporosis denosumab.

Researchers believe that denosumab works by blocking the molecule needed to convert osteomorphs into osteoclasts, so that when patients receive treatment, they can develop osteomorphs. When treatment is stopped, there is a flood of osteoclasts, causing a sudden rupture of bone tissue.

Happy To Assist You

Contact Images

We will be happy to help you find what you need. Please call us or write to us:

Contact us

mapicon
Sales Office (U.S.):
Worldwide Market Reports, 1001 4th Ave, #3200 Seattle, WA 98154, U.S.

mapicon+1-415-871-0703

mapicon
Asia Pacific Intelligence Center (India):
Worldwide Market Reports, 403, 4th Floor, Bremen Business Center, Aundh, Pune, Maharashtra 411007, India.

Newsletter

Want us to send you latest updates of the current trends, insights, and more, signup to our newsletter (for alerts, special offers, and discounts).


Secure Payment By:
paymenticon

This website is secured Origin CA certificate on the server, Comodo, Firewall and Verified Sitelock Malware Protection

secureimg

© 2021 Worldwide Market Reports. All rights reserved