Acute Heart Failure (AHF) Therapeutics Market - Size, Share, Outlook, and Forecast till 2026

Acute heart failure (AHF), also known as acute decompensated heart failure or cardiac failure, is a clinical syndrome that is associated with a wide range of symptoms such as dyspnoea, orthopnoea, and lower limb swelling. Acute heart failure is the inability of the heart to pump blood at a normal rate so as to serve the needs of the body.

Acute heart failure is primary caused due to disturbance in the systolic or diastolic heart function and may also be a result of abnormal venous or arterial vasoconstriction and volume overload. Some other factors causing acute heart failure include allergic reactions, blood clot in the lungs, complication resulting from cardiopulmonary bypass surgeries, heart attacks, severely irregular heartbeats, and virus attacking the heart.

Research has been conducted over the recent past to develop effective therapies for acute heart failure. Some of the major therapies developed for treatment of this disease include Beta blockers, Clevidipine, and Sodium nitroprusside class of drugs.

Beta blockers are beta-adrenergic blocking agents, which help reduce blood pressure by blocking the release of hormone adrenaline. This class of drug helps slow down heart beats, thereby reducing blood pressure and improving blood flow. CLEVIPREX, also known as clevidipine, is a dihydropyridine calcium channel blocker specifically used to reduce blood pressure, in cases when oral therapy cannot be provided or has no effect.

According to American Heart Association (AHA), 2018, the prevalence of heart failure is increasing among the aging population and is estimated at 6.5 million adults. The major risk factors for HF are CHD, hypertension, and diabetes. The increasing prevalence of heart failure, in turn, is expected to increase the demand for therapeutics or drugs to treat this condition. Thus, the acute heart failure therapeutics market is expected to witness significant growth in the near future.

Growing urbanization coupled with increasing inclination towards sedentary lifestyle in turn, is increasing prevalence of diabetes. This is increasing the risk of acute heart failure among the diabetic population, which in turn, is increasing the demand for treatment of such a condition. This in turn, is boosting growth of the acute heart failure therapeutics market.

Some therapies for treatment of acute heart failure are associated with side effects such as fatigue, cold hands or feet, and weight gain, which in turn, pose as major factors restraining growth of the acute heart failure therapeutics market.

Major players operating in the global acute heart failure therapeutics market include Pfizer, GlaxoSmithKline plc. Novartis International AG, Biovail, Bristol Mayers Squibb Company, MSD, AstraZenica, Abiomed Inc., Symplmed, Berlin Heart GmbH, and Biotronik SE & Co. KG.

In March 2013, Pfizer Inc. announced results from the REMINDER trial for its new drug INSPRA, which shows significant reductions in risk for acute heart failure. INSPRA is a steroid nucleus-based mineralcorticoid receptor (MR) antagonist with a higher degree of selectivity than spironolactone. This drug is indicated for use in patients suffering from left ventricular (LV) systolic dysfunction and congestive heart failure after an acute myocardial infarction.

Report includes chapters which deeply display the following deliverable about industry:

• Acute Heart Failure (AHF) Therapeutics Market Research Objective and Assumption
• Acute Heart Failure (AHF) Therapeutics Market Purview - Report Description, Executive Summary, and Coherent Opportunity Map (COM)
• Acute Heart Failure (AHF) Therapeutics Market Dynamics, Regulations, and Trends Analysis - Market Dynamics, Regulatory Scenario, Industry Trend, Merger and Acquisitions, New system Launch/Approvals, Value Chain Analysis, Porter’s Analysis, and PEST Analysis
• Global Acute Heart Failure (AHF) Therapeutics Market, By Regions
• Acute Heart Failure (AHF) Therapeutics Market Competition by Manufacturers including Production, Share, Revenue, Average Price, Manufacturing Base Distribution, Sales Area and Product Type.
• Acute Heart Failure (AHF) Therapeutics Market Manufacturers Profiles/Analysis including Company Basic Information, Manufacturing Base and Its Competitors.
• Acute Heart Failure (AHF) Therapeutics Market Manufacturing Cost Analysis including Key Raw Materials and Key Suppliers of Raw Materials.
• Industrial Chain, Sourcing Strategy and Downstream Buyers including Upstream Raw Materials Sourcing and Downstream Buyers
• Marketing Strategy Analysis, Distributors/Traders including Marketing Channel, Market Positioning and Distributors/Traders List.
• Market Effect Factors Analysis including Technology Progress/Risk, Consumer Needs/Customer Preference Change and Economic/Political Environmental Change.
• Acute Heart Failure (AHF) Therapeutics Market Forecast including Production, Consumption, Import and Export Forecast by Type, Applications and Region.
• Research Findings and Conclusion

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